DOI: https://doi.org/10.30978/UTJ2018-3-4-73

Інгібітор фактора міграції макрофагів при гострому інфаркті міокарда

M. P. Kopytsya, T. Y. Storozhenko

Анотація


Інгібітор фактора міграції макрофагів (МІФ) — плейотропний прозапальний цитокін, який бере участь у розвитку багатьох гострих та хронічних запальних захворювань, в тому числі серцево-судинних. Виявлено тісний зв’язок між МІФ і гострим інфарктом міокарда (ГІМ). Водночас невідомо, якою мірою ранні циркулюючі рівні МІФ корелюють з початком і ступенем інфаркту міокарда. В огляді представлено аналіз даних останніх клінічних та експериментальних досліджень щодо ролі МІФ у патогенетичних механізмах ГІМ.

Ключові слова


інгібітор фактора міграції макрофагів; гострий інфаркт міокарда; серцево-судинні захворювання

Повний текст:

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Посилання


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