Антиоксидантна активність у пацієнтів із хронічним обструктивним захворюванням легень та ішемічною хворобою серця
DOI:
https://doi.org/10.30978/UTJ2018-3-4-62Ключові слова:
система оксиданти/антиоксиданти, загальна антиоксидантна активність, сигаретний дим, хронічне обструктивне захворювання легень, ішемічна хвороба серця, препарати антиоксидантної діїАнотація
Вивчено нові дані про роль антиоксидантної системи в механізмах патогенезу хронічного обструктивного захворювання легень (ХОЗЛ) і в поєднанні з ішемічною хворобою серця (ІХС). Визначено ефективний мікрометод оцінки загальної антиоксидантної активності в плазмі крові людини. Зауважено неоднозначний характер змін системи оксиданти/антиоксиданти при ХОЗЛ, а також на тлі впливу сигаретного диму. Показано, що при загостренні кардіореспіраторної патології реакції вільнорадикального окислення посилюються, але з віком спостерігається неспецифічність змін. Наведено дані про ефективність різних препаратів антиоксидантної дії в лікуванні ХОЗЛ і в поєднанні з ІХС. Окреслено перспективи розвитку досліджень в індивідуальному підборі лікарських засобів.Посилання
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